This is a common problem of Range Research and it may be caused by 2 factors. a) You don't have enough space in your disk. b) Your database is too big.
If you have space in your disk and you're working with a large database, you have to run range research reports separately. Note that you have different pre-made reports in range research folders: 'Preflop' and 'Single Reports'. These reports are from the main popup, but distributed as a single reports by action. So, if you are experiencing the problem of taking too much time in saving results into database (too much hours), you have to run your reports separately.
Simply select your desired report, then put your Base stat preferences: VPIP, PFR, gap, Hands, etc.